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| Research article summary (published 16 Nov 2008): |
Optic nerve sheath meningiomas--non-surgical treatment.
Full Abstract
AIMS: Optic nerve sheath meningiomas typically present with unilateral visual deterioration. Here, a single centre's experience with radiotherapy aimed at local control and visual stabilisation is presented. MATERIALS AND METHODS: The meningioma database within the Radiation Oncology Department, Prince of Wales Hospital was audited for patients whose meningiomas took origin from the optic nerve sheath. Excluded from this evaluation was any patient whose meningioma secondarily involved the optic nerve. Where vision was not a consideration, treatment was given by stereotactic radiosurgery for patients with retained vision. The remaining patients were treated by fractionated radiotherapy, predominately via a stereotactic approach. The main end points were: lack of radiological progression of the tumour and maintenance of preradiotherapy vision. RESULTS: There were 15 eligible patients, one patient with neurofibromatosis had bilateral optic nerve involvement; thus, 16 optic nerves were treated. Women (10) outnumbered men (five) and the age range was 7-74 years. One patient progressed outside the volume treated (for a geographical failure) with no infield progression. This patient became blind, was re-treated by stereotactic radiosurgery, had tumour control and vision improved. Thus, for 17 optic nerves (or part thereof) treated, all patients ultimately had local control (100%) with worsening of vision only occurring in one patient. No other late morbidity was present for any patient. CONCLUSION: Optic nerve sheath meningiomas have high local control rates and preservation of vision with radiotherapy.
Author information
Author/s: Smee, R I (RI); Schneider, M (M); Williams, J R (JR);
Affiliation: Department of Radiation Oncology, The Prince of Wales Cancer Centre, Randwick, New South Wales, Australia. robert.smee(-atsign-)sesiahs.health.nsw.gov.au
Journal and publication information
Publication Type: Case Reports; Journal Article
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) (Clin Oncol (R Coll Radiol)), published in England. (Language: eng)
Reference: 2009-Feb; vol 21 (issue 1) : pp 8-13
Dates: Created 2009/01/12; Completed 2009/03/27;
PMID: 19019641, status: MEDLINE (last retrieval date: 3/27/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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