 |
| Research article summary (published 7 Dec 2008): |
Simultaneous cannabis and tobacco use and cannabis-related outcomes in young women.
Full Abstract
Compared to those who reported a lifetime co-occurrence of cannabis and tobacco use, individuals who report simultaneous use of cannabis and tobacco are more likely to also report higher rates of substance-related problems and psychopathology. In a sample of young women, we examine (a) co-occurring use, or whether regular cigarette smoking is associated with increased cannabis involvement and (b) simultaneous use, a special form of co-occurring use where cannabis and cigarettes are typically used on the same occasion to test whether those who use cannabis and tobacco simultaneously are also more likely to report greater cannabis involvement and (c) the extent to which latent genetic and environmental factors contribute to simultaneous use in those with a history of co-occurring cannabis use and regular cigarette smoking. Women (N=3427) who report regular cigarette smoking are 4.5-9.5 times more likely to report co-occurring cannabis use and other stages of cannabis involvement, including DSM-IV cannabis abuse and dependence. In those women who report co-occurring regular cigarette smoking and lifetime cannabis use (N=1073), simultaneous use of cannabis and tobacco was associated with increased likelihood of negative cannabis-related outcomes. Simultaneous users were 1.6 times more likely to meet criteria for DSM-IV cannabis abuse, even after controlling for early covariates and for prior stages of cannabis involvement. Simultaneous use was not heritable, and twin similarity was attributable to shared environmental factors (31%). While our study does not determine causality between simultaneous tobacco-cannabis use and cannabis involvement, results indicate that simultaneous use is potentially a marker for more severe psychosocial consequences associated with cannabis use.
Author information
Author/s: Agrawal, Arpana (A); Lynskey, Michael T (MT); Madden, Pamela A F (PA); Pergadia, Michele L (ML); Bucholz, Kathleen K (KK); Heath, Andrew C (AC);
Affiliation: Washington University School of Medicine, Department of Psychiatry, St. Louis, MO 63110, USA. arpana(-atsign-)wustl.edu
Grants: AA07728 (Agency:NIAAA NIH HHS) ; AA09022 (Agency:NIAAA NIH HHS) ; AA11998 (Agency:NIAAA NIH HHS) ; AA12640 (Agency:NIAAA NIH HHS) ; DA023668 (Agency:NIDA NIH HHS) ; DA12854 (Agency:NIDA NIH HHS) ; DA14363 (Agency:NIDA NIH HHS) ; DA18267 (Agency:NIDA NIH HHS) ; DA18660 (Agency:NIDA NIH HHS) ; HD49024 (Agency:NICHD NIH HHS)
Journal and publication information
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Twin Study
Journal: Drug and alcohol dependence (Drug Alcohol Depend), published in Ireland. (Language: eng)
Reference: 2009-Apr; vol 101 (issue 1-2) : pp 8-12
Dates: Created 2009/02/23; Completed 2009/05/21;
PMID: 19081202, status: MEDLINE (last retrieval date: 5/21/2009, IMS Date: 21 May 2009 00:00:00)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.