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| Research article summary (published 20 Dec 2009): |
Laser treatment of benign prostatic hyperplasia in patients on oral anticoagulant therapy: a review.
Full Abstract
We assessed the therapeutic efficacy and safety of laser prostatectomy (LP) for treating benign prostatic hyperplasia (BPH) in patients on oral anticoagulation. We systematically reviewed previous reports, using the Pubmed database and bibliographies of retrieved articles and reviews. The oral anticoagulation included coumarin derivatives and platelet-aggregation inhibitors (PAI). Previous studies do not allow the establishment of definitive conclusions for managing patients on oral anticoagulation and who require BPH surgery. No randomized studies are available. Nevertheless, compared to transurethral resection of the prostate (TURP), LP seems to decrease the risk of haemorrhage in patients taking PAI or coumarin derivatives. Therefore, LP is a useful alternative to TURP for managing patients on oral anticoagulation, and could be proposed as the first intention for those patients. Continuing PAI during the procedure is feasible. A replacement of coumarin derivatives by low molecular weight heparin is preferable. No conclusion can be reached on the preferred type of laser technique to treat these patients, but data on laser enucleation is much less abundant and conclusive than that on laser vaporization.
Author information
Author/s: Descazeaud, Aurélien (A); Robert, Gregoire (G); Azzousi, Abdel Rahmene (AR); Ballereau, Charles (C); Lukacs, Bertrand (B); Haillot, Olivier (O); Dumonceau, Olivier (O); Devonec, Marian (M); Fourmarier, Marc (M); Saussine, Christian (C); de la Taille, Alexandre (A); Committee for lower urinary tract symptoms of the French Association of Urology;
Affiliation: Department of Urology, CHU Limoges, Hôpital Dupuytren, Limoges, France. aurelien.descazeaud(-atsign-)chu-limoges.fr
Journal and publication information
Publication Type: Journal Article; Review
Journal: BJU international (BJU Int), published in England. (Language: eng)
Reference: 2009-May; vol 103 (issue 9) : pp 1162-5
Dates: Created 2009/04/30; Completed 2009/05/28;
PMID: 19154457, status: MEDLINE (last retrieval date: 5/28/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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