Research article summary (published 23 Feb 2009):

Changes in artistic style and behaviour in Parkinson's disease: dopamine and creativity.

Full Abstract

We present a PD patient in whom dopamine agonists awoke a hidden creativity that led to a gradual increase in painting productivity evolving to a disruptive impulsive behaviour that shared many features with punding. A dramatic change in painting style related to a more emotional experience during the process of creation developed after treatment onset. This case suggests that changes in creativity in PD seem to be related to dopaminergic imbalance in the limbic system.

Author information

Author/s: Kulisevsky, Jaime (J); Pagonabarraga, Javier (J); Martinez-Corral, Mercè (M);

Affiliation: Movement Disorders Unit, Neurology Department, Sant Pau Hospital, Autonomous University of Barcelona, Sant Antoni Maria Claret 167, Barcelona 08025, Spain. jkulisevsky(-atsign-)santpau.es

Journal and publication information

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

Journal: Journal of neurology (J Neurol), published in Germany. (Language: eng)

Reference: 2009-May; vol 256 (issue 5) : pp 816-9

Dates: Created 2009/05/19; Completed 2009/08/21;

PMID: 19240966, status: MEDLINE (last retrieved date: 8/21/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Antiparkinson Agents - administration & dosage; adverse effects Arm - innervation; physiopathology Art Benzothiazoles - administration & dosage; adverse effects Brain - drug effects; metabolism; physiopathology Creativeness Depressive Disorder - drug therapy; etiology; psychology Dopamine - metabolism Dopamine Agonists - administration & dosage; adverse effects Dose-Response Relationship, Drug Drug Therapy, Combination

Drug Therapy, Combination Ergolines - administration & dosage; adverse effects Humans Levodopa - administration & dosage Male Mental Disorders - chemically induced; physiopathology; psychology Middle Aged Motor Skills - drug effects; physiology Obsessive Behavior - chemically induced; physiopathology; psychology Paintings Parkinson Disease - drug therapy; physiopathology; psychology

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Antiparkinson Agents (0) ; Benzothiazoles (0) ; Dopamine Agonists (0) ; Ergolines (0) ; Levodopa (0) ; pramipexol (104632-26-0) ; cabergoline (81409-90-7)

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