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| Research article summary (published 27 Feb 2009): |
Optic nerve and chiasmal germinoma.
Full Abstract
A 15-year-old boy presented with visual acuity of 20/200 OD and no light perception OS. The anterior segment of the left eye showed a relative afferent pupillary defect. A large (4.5 x 4.5 x 2.0 mm) infiltrative optic nerve head lesion with dilated vessels was seen OS with disc pallor OD. MRI of the brain and orbit revealed lobulated optic nerve thickening and chiasm. A biopsy revealed features consistent with germinoma and was positive for marker placental alkaline phosphatase. Systemic examination, chest x-ray, abdominal ultrasound, cerebrospinal fluid, and serology were normal. He received 27 Gy to the craniospinal region followed by a boost of 27 Gy to the left optic nerve. Eight months postirradiation, vision stabilization was achieved with 20/200 OD and light perception with inaccurate projection of rays OS.
Author information
Author/s: Rath, Suryasnata (S); Vemuganti, Geeta K (GK); Biswas, Ghanashyam (G); Mod, Hemendra (H);
Affiliation: Ocular Oncology Service, L.V. Prasad Eye Institute, Bhubaneswar, India. suryasnata(-atsign-)lvpei.org
Journal and publication information
Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
Journal: Ophthalmic plastic and reconstructive surgery (Ophthal Plast Reconstr Surg), published in United States. (Language: eng)
Reference: -2009 Mar-Apr; vol 25 (issue 2) : pp 161-3
Dates: Created 2009/03/20; Completed 2009/06/16;
PMID: 19300174, status: MEDLINE (last retrieval date: 6/16/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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