Sequelae of closed craniocerebral trauma and the efficacy of piracetam in its treatment in adolescents.

Full Abstract

The efficacy of piracetam in treating the sequelae of moderate and severe closed craniocerebral trauma (CCT) in adolescents was evaluated in studies of 42 patients aged 12-18 years who had suffered CCT 1.5-5 years prior to the study. Adolescents of the experimental group (20 individuals) received piracetam (Nootropil) at doses of 40-50 mg/kg (daily daily 1600-2400 mg) for one month; patients of group 2 (22 individuals) served as controls. Piracetam was found to have positive therapeutic effects on impairments to higher mental (memory, attention, executive) and motor (coordination) functions and on measures of the speeds of cognitive and motor operations.

Author information

Author/s: Zavadenko, N N (NN); Guzilova, L S (LS);

Affiliation: Department of Neurology and Neurosurgery, Faculty of Pediatrics, Russian State Medical University, Moscow, Russia.

Journal and publication information

Publication Type: Journal Article

Journal: Neuroscience and behavioral physiology (Neurosci Behav Physiol), published in United States. (Language: eng)

Reference: 2009-May; vol 39 (issue 4) : pp 323-8

Dates: Created 2009/04/14; Completed 2009/08/12;

PMID: 19340573, status: MEDLINE (last retrieved date: 8/21/2009)

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