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| Research article summary (published 30 Mar 2009): |
Personality traits, depression, and objectively measured adherence to once-daily prostaglandin analog medication in glaucoma.
Full Abstract
PURPOSE: To investigate the influence of personality traits, depression, and training on objectively measured adherence to once-daily prostaglandin analog medication. METHODS: Adherence was measured with the Travalert Dosing Aid on 58 consecutive, regularly followed-up glaucoma patients already on self-administered travoprost. Before the 3-month data-collection period all patients received training on use of the device. Psychologic characteristics were measured using the State-Trait Anxiety Inventory, Eysenck Personality Questionnaire, and Beck Hopeless Scale and Depression Inventory. An adherent day was defined as travoprost instillation at 9 PM +/-2 hours. RESULTS: Adherence was 77% for the total period. Social desirability was higher than normal (U test, P<0.0001). Seven patients (12.1%) showed mild-to-moderate depression, which was not significantly associated with decreased adherence (Kruskal-Wallis test, P=0.071). Severity of glaucoma, number of ocular and systemic medications, satisfaction with the recording device, and socio-economic characteristics had no influence on adherence. CONCLUSIONS: Objectively measured adherence to once-daily prostaglandin analog medication was good, and not influenced by treatment characteristics or patient factors including mild-to-moderate depression. The elevated social desirability suggests that self-reported adherence is not a reliable measure of adherence in glaucoma.
Author information
Author/s: Holló, Gábor (G); Kóthy, Péter (P); Géczy, Anna (A); Vargha, Péter (P);
Affiliation: Department of Ophthalmology, Semmelweis University, Budapest, Hungary.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Journal of glaucoma (J Glaucoma), published in United States. (Language: eng)
Reference: -2009 Apr-May; vol 18 (issue 4) : pp 288-92
Dates: Created 2009/04/14; Completed 2009/07/01;
PMID: 19365193, status: MEDLINE (last retrieval date: 7/1/2009, IMS Date: 01 Jul 2009 00:00:00)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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