Quantifying nonlinear anisotropic elastic material properties of biological tissue by use of membrane inflation.

Full Abstract

Determination of material parameters for soft tissue frequently involves regression of material parameters for nonlinear, anisotropic constitutive models against experimental data from heterogeneous tests. Here, parameter estimation based on membrane inflation is considered. A four parameter nonlinear, anisotropic hyperelastic strain energy function was used to model the material, in which the parameters are cast in terms of key response features. The experiment was simulated using finite element (FE) analysis in order to predict the experimental measurements of pressure versus profile strain. Material parameter regression was automated using inverse FE analysis; parameter values were updated by use of both local and global techniques, and the ability of these techniques to efficiently converge to a best case was examined. This approach provides a framework in which additional experimental data, including surface strain measurements or local structural information, may be incorporated in order to quantify heterogeneous nonlinear material properties.

Author information

Author/s: Bischoff, Jeffrey E (JE); Drexler, Elizabeth S (ES); Slifka, Andrew J (AJ); McCowan, Christopher N (CN);

Affiliation: Zimmer, Inc., Warsaw, IN, USA. jeff.bischoff(-atsign-)zimmer.com

Journal and publication information

Publication Type: Journal Article

Journal: Computer methods in biomechanics and biomedical engineering (Comput Methods Biomech Biomed Engin), published in England. (Language: eng)

Reference: 2009-Jun; vol 12 (issue 3) : pp 353-69

Dates: Created 2009/04/27; Completed 2009/06/18;

PMID: 19396729, status: MEDLINE (last retrieval date: 6/18/2009, IMS Date: 18 Jun 2009 00:00:00)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

This article has not been indexed for related articles as yet, however you can still use the live related article search links below.

See 100+ related articles.

See a large map of 100+ related articles.