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| Research article summary (published 9 May 2009): |
Dopamine, reinforcement learning, and addiction.
Full Abstract
Dopamine is intimately linked with the modes of action of drugs of addiction. However, although its role in the initiation of drug abuse seems relatively uncomplicated, its possible involvement in the development of compulsive drug taking, and indeed vulnerability and relapse, is less clear. We first describe a modern reinforcement learning view of affective control, focusing on the roles for dopamine. We then use this as a framework to sketch various notions of the neuromodulator's possible participation in initiation and compulsion. We end with some pointers towards future theoretical developments.
Author information
Author/s: Dayan, P (P);
Affiliation: Gatsby Computational Neuroscience Unit, UCL, London, UK. dayan(-atsign-)gatsby.ucl.ac.uk
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal: Pharmacopsychiatry (Pharmacopsychiatry), published in Germany. (Language: eng)
Reference: 2009-May; vol 42 Suppl 1 (issue ) : pp S56-65
Dates: Created 2009/05/12; Completed 2009/07/01;
PMID: 19434556, status: MEDLINE (last retrieval date: 7/1/2009, IMS Date: 01 Jul 2009 00:00:00)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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