Research article summary (published 29 Jan 2009):

Diurnal rhythms in seizures detected by intracranial electrocorticographic monitoring: an observational study.

Full Abstract

Few studies have evaluated human seizure occurrence over the 24-hour day, and only one group has employed intracranial electrocorticography monitoring to record seizures. Circadian patterns in seizures may have important implications in diagnosis and therapy and provide opportunities in research. We have analyzed spontaneous seizures in 33 consecutive patients with long-term intracranial EEG and video monitoring. Several aspects of seizures were noted, including time of day, origin, type, and behavioral state (sleeping/awake). We recorded 450 seizures that showed an uneven distribution over the day, depending on lobe of origin: temporal lobe seizures occurred preferentially between 1100 and 1700 hours, frontal seizures between 2300 and 0500 hours, and parietal seizures between 1700 and 2300 hours. In the awake state, larger proportions of clinical seizures were seen from 0500 to 1100 hours and from 1700 to 2300 hours. During sleep, larger proportions occurred from 1100 to 1700 hours and from 2300 to 0500 hours. Our results suggest that seizures from different brain regions have a strong tendency to occur in different diurnal patterns.

Author information

Author/s: Hofstra, Wytske A (WA); Spetgens, Willy P J (WP); Leijten, Frans S S (FS); van Rijen, Peter C (PC); Gosselaar, Peter (P); van der Palen, Job (J); de Weerd, Al W (AW);

Affiliation: Department of Clinical Neurophysiology and Sleep Centre SEIN Zwolle, Zwolle, The Netherlands. whofstra(-atsign-)sein.nl

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Epilepsy & behavior : E&B (Epilepsy Behav), published in United States. (Language: eng)

Reference: 2009-Apr; vol 14 (issue 4) : pp 617-21

Dates: Created 2009/05/15; Completed 2009/08/07;

PMID: 19435581, status: MEDLINE (last retrieval date: 8/21/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adolescent Adult Age Factors Circadian Rhythm - physiology Electroencephalography - methods Female Humans

Male Middle Aged Monitoring, Physiologic - methods Obsessive Behavior Seizures - physiopathology Video Recording - methods Young Adult

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