Cognitive neuropsychology of HIV-associated neurocognitive disorders.

Full Abstract

Advances in the treatment of the human immunodeficiency virus (HIV) have dramatically improved survival rates over the past 10 years, but HIV-associated neurocognitive disorders (HAND) remain highly prevalent and continue to represent a significant public health problem. This review provides an update on the nature, extent, and diagnosis of HAND. Particular emphasis is placed on critically evaluating research within the realm of cognitive neuropsychology that aims to elucidate the component processes of HAND across the domains of executive functions, motor skills, speeded information processing, episodic memory, attention/working memory, language, and visuoperception. In addition to clarifying the cognitive mechanisms of HAND (e.g., impaired cognitive control), the cognitive neuropsychology approach may enhance the ecological validity of neuroAIDS research and inform the development of much needed novel, targeted cognitive and behavioral therapies.

Author information

Author/s: Woods, Steven Paul (SP); Moore, David J (DJ); Weber, Erica (E); Grant, Igor (I);

Affiliation: Department of Psychiatry (0847), School of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA. spwoods(-atsign-)ucsd.edu

Grants: MH62512 (Agency:NIMH NIH HHS) ; MH73419 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

Journal: Neuropsychology review (Neuropsychol Rev), published in United States. (Language: eng)

Reference: 2009-Jun; vol 19 (issue 2) : pp 152-68

Dates: Created 2009/06/04; Completed 2009/09/24;

PMID: 19462243, status: MEDLINE (last retrieval date: 9/24/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.