Research article summary (published 29 Apr 2009):

[Choroidal metastasis from a breast carcinoma. Diagnosis and follow-up with optical coherence tomography and fluorescein angiography and autofluorescence with HRA-II (Heidelberg Retina Angiograph)]

(Metástasis coroideas de carcinoma de mama. Diagnóstico y seguimiento mediante tomografía de coherencia óptica y angiofluoresceingrafía y autofluorescencia con HRA-II (Heidelberg Retina Angiograph).)

Full Abstract

CLINICAL CASE: A 69-year-old woman developed choroidal metastasis from a breast carcinoma 2 years after the initial diagnosis, surgery and chemotherapy. After treatment with palliative chemotherapy and external radiotherapy, we used fluorescein angiography (FA) and optical coherence tomography (OCT) to evaluate the resolution of the serous retinal detachment, as well as a later relapse in the optic nerve. DISCUSSION: OCT is useful in the follow-up of choroidal metastasis after treatment. However, OCT imaging is limited by the initial choroidal location of metastasis. The autofluorescence can detect exudative tumoral activity even without obvious changes in OCT or FA.

Author information

Author/s: Pérez-Alvarez, M J (MJ); Arriola-Villalobos, P (P); Reche-Frutos, J (J); García-Sánchez, J (J);

Affiliation: Hospital Clínico San Carlos, Unidad de Retina, Madrid, Spain. mjperezalv(-atsign-)hotmail.com

Journal and publication information

Publication Type: Case Reports; English Abstract; Journal Article

Journal: Archivos de la Sociedad Española de Oftalmología (Arch Soc Esp Oftalmol), published in Spain. (Language: spa)

Reference: 2009-May; vol 84 (issue 5) : pp 267-70

Dates: Created 2009/05/25; Completed 2009/09/04;

PMID: 19466689, status: MEDLINE (last retrieval date: 9/4/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage; therapeutic use Breast Neoplasms - drug therapy; pathology; surgery Carcinoma, Ductal, Breast - complications; diagnosis; drug therapy; radiotherapy; secondary Choroid Neoplasms - complications; diagnosis; drug therapy; radiotherapy; secondary Combined Modality Therapy Cyclophosphamide - administration & dosage; analogs & derivatives Doxorubicin - administration & dosage Female

Fluorescein Angiography Fluorouracil - administration & dosage Humans Lymph Node Excision Mastectomy, Radical Optic Nerve Neoplasms - secondary Palliative Care Retinal Detachment - etiology Tomography, Optical Coherence

Associated Chemicals: CAF protocol (0) ; trofosfamide (22089-22-1) ; Doxorubicin (23214-92-8) ; Cyclophosphamide (50-18-0) ; Fluorouracil (51-21-8)

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