[New antiemetic strategies - not only in oncology]

(Neue antiemetische Strategien - nicht nur in der Onkologie.)

Full Abstract

Nausea and vomiting are common symptoms in daily clinical practice. For appropriate diagnostics the knowledge of the pathopysiologic origin of nausea and vomiting is indispensable. Furthermore the diagnostic pathway usually has to be approached by an interdisciplinary team. Due to the broad spectrum of emetogenic causes several symptom-based treatment strategies are nowadays available. These include several kinds of antiemetics with different mechanisms of action and with an varying antiemetic potential. The antiemetic strategy is based on individual patient factors as well as on the receptor specific mechanism of action of the antiemetic drug and also the expected side effects. A number of modern antiemetic agents are available for the management of nausea and vomiting, including 5-HT(3)-receptor antagonists and NK(1) receptor antagonists. However, other conventional antiemetic drugs are still in use and should not be underestimated.

Author information

Author/s: Jordan, K (K); Müller, F (F); Schmoll, H J (HJ);

Affiliation: Klinik für Innere Medizin IV, Universitätsklinikum Halle, Ernst-Grube-Strasse 40, 06120, Halle, Deutschland. karin.jordan(-atsign-)medizin.uni-halle.de

Journal and publication information

Publication Type: English Abstract; Journal Article; Review

Journal: Der Internist (Internist (Berl)), published in Germany. (Language: ger)

Reference: 2009-Jul; vol 50 (issue 7) : pp 887-94

Dates: Created 2009/08/12; Completed 2009/10/28;

PMID: 19484194, status: MEDLINE (last retrieved date: 10/28/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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