Basophils trump dendritic cells as APCs for T(H)2 responses.

Full Abstract

Dendritic cells are best known as antigen-presenting cells that initiate adaptive immune responses. Three new papers suggest that basophils initiate allergen- and helminth-driven CD4+ T helper type 2 responses by functioning as antigen-presenting cells in draining lymph nodes.

Author information

Author/s: Wynn, Thomas A (TA);

Journal and publication information

Publication Type: News

Journal: Nature immunology (Nat Immunol), published in United States. (Language: eng)

Reference: 2009-Jul; vol 10 (issue 7) : pp 679-81

Dates: Created 2009/06/18; Completed 2009/09/18; Revised 2009/10/05;

PMID: 19536189, status: MEDLINE (last retrieval date: 10/6/2009, IMS Date: )

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