 |
| Research article summary (published 29 Sep 2009): |
No association between vitamin D receptor polymorphisms and coronary artery disease in a Chinese population.
Full Abstract
The clinical features suggest that genetic factors may have a strong influence on susceptibility to coronary artery disease (CAD). The aim of this study was to investigate the association between FokI (rs2228570) and BsmI (rs1544410) of the vitamin D receptor (VDR) gene polymorphisms and patients with CAD in a Chinese population. One hundred and fifty-two CAD patients and 212 healthy controls were genotyped for the FokI and BsmI polymorphisms in VDR gene using polymerase chain reaction-restriction fragment length polymorphism. No significant differences were observed in the genotype and allele frequencies of the FokI and BsmI polymorphisms between the cases and controls (For FokI: odds ratio = 1.11, 95% confidence interval 0.83-1.50; for BsmI: odds ratio = 0.74, 95% confidence interval 0.44-1.23). There was no significant difference in the genotype distribution or the allele frequencies of VDR FokI and BsmI between two groups in a Chinese population.
Author information
Author/s: Pan, Xin-Min (XM); Li, Dong-Ri (DR); Yang, Lan (L); Wang, En-Yin (EY); Chen, Tian-Yi (TY); Liu, Ya-Ju (YJ); Liu, Min (M); Liao, Zhi-Gang (ZG);
Affiliation: Department of Forensic Pathology, West China School of Preclinical and Forensic Medicine, Sichuan University , Chengdu, Peoples' Republic of China .
Journal and publication information
Publication Type: Journal Article
Journal: DNA and cell biology (DNA Cell Biol), published in United States. (Language: eng)
Reference: 2009-Oct; vol 28 (issue 10) : pp 521-5
Dates: Created 2009/09/23; Completed 2009/10/26;
PMID: 19563249, status: MEDLINE (last retrieval date: 10/26/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
These are the highest related articles currently in the database:
- Vitamin D receptor alleles and C-reactive protein in hemodialysis patients.
30 Dec 2007 - [Polymorphisms of vitamin D receptor gene]
27 Feb 2002 - Association of vitamin D receptor gene polymorphism with sporadic breast cancer in Taiwanese patients. 29 Jun 2002
- Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in Chilean subjects: a case-parent study. 30 Dec 2003
- [Vitamin D receptor gene polymorphisms in female adolescent idiopathic scoliosis patients] 3 Jun 2007
- BsmI polymorphism of the vitamin D receptor gene in patients with the fulminant course of rosacea conglobata (rosacea fulminans). 28 Feb 2004
- Meta-analysis of vitamin D receptor polymorphisms and pulmonary tuberculosis risk. 29 Sep 2005
- Vitamin D receptor gene variants of BsmI, ApaI, TaqI, and FokI polymorphisms in spinal tuberculosis. 30 Dec 2003
- [Association between vitamin D receptor gene polymorphism and vitamin D deficiency rickets] 30 Mar 2006
- [Vitamin D receptor gene polymorphisms and vitamin D deficiency rickets] 30 Jan 2006
Related Article Map
2/27/2002
12/30/2007
Higher Relevance Score (100)
Lower Relevance Score (80)
Legend: - FREE Full text Article. - Abstract only. - Title only. More help.
See a large map of 100+ related articles.