Research article summary (published 29 Apr 2009):

[Osmotic behavior of mouse embryonic cells subjected to hypotonic shock]

Full Abstract

Osmotic adaptation in a blastomere of mouse embryo has been studied by the direct measurement of the cell volume using laser scanning microscopy microtomography followed by quantitative 3D reconstruction. Embryonic cells subjected to hypotonic shock first swelled and then returned to the initial size. At the beginning of osmotic stress, the swelling occurred by the van't Hoff equation with the water permeability coefficient (L(p)) of 0.4 micro x min(-1) atm(-1). The phase of the regulatory volume decrease was not abolished by Na+/K(+)-ATPase inhibition.

Author information

Author/s: Pogorelov, A G (AG); Pogorelova, V N (VN);

Journal and publication information

Publication Type: English Abstract; Journal Article; Research Support, Non-U.S. Gov't

Journal: Biofizika (Biofizika), published in Russia (Federation). (Language: rus)

Reference: -2009 May-Jun; vol 54 (issue 3) : pp 482-7

Dates: Created 2009/07/02; Completed 2009/08/11;

PMID: 19569509, status: MEDLINE (last retrieval date: 8/21/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Blastomeres - cytology; metabolism Cell Membrane Permeability Cell Size Hypotonic Solutions Mice

Mice, Inbred C57BL Mice, Inbred CBA Microscopy, Confocal Osmotic Pressure Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors Water - metabolism

Associated Chemicals: Hypotonic Solutions (0) ; Water (7732-18-5) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9)

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