 |
| Research article summary (published 3 Aug 2009): |
Electrophysiological correlates of reduced pain perception after theta-burst stimulation.
Full Abstract
In an earlier study, we reported the antinociceptive effects of a special repetitive transcranial magnetic stimulation paradigm: continuous theta-burst stimulation (cTBS), when applied to human motor cortex. Here, we investigated whether the reduced subjective pain perception of 10 healthy individuals could be measured by changes in laser-evoked potentials, a reflection of pain related activations in the operculoinsular and midcingulate cortex. To minimize the effect of habituation during repeated laser stimulation, a bioadaptive design was used. However, both pain ratings and laser-evoked potential amplitudes were reduced after real and sham cTBS. When compared with sham stimulation, cTBS resulted in a significantly greater diminution of pain ratings and N2-P2 amplitudes on the hand contralateral to the site of motor cortex stimulation.
Author information
Author/s: Csifcsak, Gabor (G); Nitsche, Michael A (MA); Baumgärtner, Ulf (U); Paulus, Walter (W); Treede, Rolf-Detlef (RD); Antal, Andrea (A);
Affiliation: Department of Clinical Neurophysiology, Georg-August University, Göttingen, Germany.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Neuroreport (Neuroreport), published in England. (Language: eng)
Reference: 2009-Aug; vol 20 (issue 12) : pp 1051-5
Dates: Created 2009/07/10; Completed 2009/09/29;
PMID: 19590390, status: MEDLINE (last retrieval date: 9/29/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
These are the highest related articles currently in the database:
- Transcranial magnetic stimulation for pain control. Double-blind study of different frequencies against placebo, and correlation with motor cortex stimulation efficacy.
3 Jun 2006 - Somatotopic organization of the analgesic effects of motor cortex rTMS in neuropathic pain. 10 Dec 2006
- Motor cortex stimulation for chronic non-malignant pain: current state and future prospects. 30 Dec 2006
- Effects of 1-Hz repetitive transcranial magnetic stimulation on acute pain induced by capsaicin. 30 Dec 2003
- Epidural motor cortex stimulation with functional imaging guidance. 13 Sep 2001
- Facilitation of A[delta]-fiber-mediated acute pain by repetitive transcranial magnetic stimulation. 20 Jun 2004
- Pain relief by rTMS: differential effect of current flow but no specific action on pain subtypes. 7 Sep 2008
- Repetitive transcranial magnetic stimulation of the motor cortex attenuates pain perception in complex regional pain syndrome type I. 10 Feb 2004
- Theta burst stimulation of the motor cortex reduces laser-evoked pain perception. 20 Jan 2008
- Dissociable modulating effect of repetitive transcranial magnetic stimulation on sensory and pain perception. 4 Feb 2006
Related Article Map
9/13/2001
9/7/2008
Higher Relevance Score (100)
Lower Relevance Score (58)
Legend: 
- FREE Full text Article. - Abstract only. 
- Title only. More help.
See a large map of 100+ related articles.