Randomized trial of a parenting intervention for very preterm infants: outcome at 2 years.

Full Abstract

OBJECTIVES: To determine the efficacy of a neonatal parenting intervention for improving development in very preterm infants. STUDY DESIGN: A cluster-randomized, controlled trial with a cross-over design and washout period was conducted in 6 neonatal centers. Two hundred thirty-three babies <32 weeks' gestation were recruited (intervention = 112; control = 121). Intervention families received weekly Parent Baby Interaction Programme (PBIP) sessions during neonatal intensive care unit admission and up to 6 weeks after discharge. Control families received standard care. All 195 infants remaining in the study at 24 months' corrected age were assessed by psychologists blinded to group allocation. RESULTS: There was no significant difference in Mental Development Index (-0.9 points; 95% CI, -5.0, 3.2) or Psychomotor Development Index (2.5; -3.3, 8.4) scores between the intervention and control groups and no significant effect of intervention on Mental Development Index or Psychomotor Development Index scores for subgroups dichotomized by gestational age (<28 weeks/> or =28 weeks), parity (1st/other child) or mother's cohabiting status (supported/unsupported). CONCLUSIONS: There was no effect of PBIP on infant development at 2 years' corrected age. Parenting interventions may be better delivered after discharge or targeted for preterm infants with high biological and social risk.

Author information

Author/s: Johnson, Samantha (S); Whitelaw, Andrew (A); Glazebrook, Cris (C); Israel, Chrissie (C); Turner, Rebecca (R); White, Ian R (IR); Croudace, Tim (T); Davenport, Franca (F); Marlow, Neil (N);

Affiliation: University of Nottingham, Nottingham, United Kingdom. s.j.johnson(-atsign-)ucl.ac.uk

Journal and publication information

Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial

Journal: The Journal of pediatrics (J Pediatr), published in United States. (Language: eng)

Reference: 2009-Oct; vol 155 (issue 4) : pp 488-94

Dates: Created 2009/09/23; Completed 2009/10/22;

PMID: 19595367, status: MEDLINE (last retrieval date: 10/22/2009, IMS Date: )

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