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| Research article summary (published 19 Jul 2009): |
Hemispheric lateralization of the corticostriatal glutamatergic system in the rat.
Full Abstract
Little is known about hemispheric lateralization of subcortical structures. Here, we show a higher expression of the subunit NR2A of the NMDA receptor mRNA in the striatum and of vGluT1 mRNA in the cingulate cortex, in the left hemisphere compared to the right one. This suggests a lateralization of the glutamatergic cortico-subcortical system, at the level of postsynaptic receptors as well as at the level of corticostriatal projections. Such lateralization could play a role in asymmetric diseases like Parkinson's disease.
Author information
Author/s: Capper-Loup, Christine (C); Rebell, Dominik (D); Kaelin-Lang, Alain (A);
Affiliation: Department of Neurology and Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Journal of neural transmission (Vienna, Austria : 1996) (J Neural Transm), published in Austria. (Language: eng)
Reference: 2009-Sep; vol 116 (issue 9) : pp 1053-7
Dates: Created 2009/08/26; Completed 2009/09/30;
PMID: 19626270, status: MEDLINE (last retrieved date: 9/30/2009)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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MeSH headings (categories)
This article was linked to the MeSH Headings (categories) shown below.
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Associated Chemicals: NR2A NMDA receptor (0) ; NR2B NMDA receptor (0) ; RNA, Messenger (0) ; Receptors, N-Methyl-D-Aspartate (0) ; Slc17a7 protein, rat (0) ; Vesicular Glutamate Transport Protein 1 (0)Related articles
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