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Research article summary (published 29 Jul 2009):

No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample.

Full Abstract

Polymorphisms within the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes are being studied for association with lithium prophylaxis in a sample of 155 Sardinian unrelated probands affected by bipolar disorder (BP). No significant association was shown between the polymorphisms of the genes studied and response to lithium treatment.

 

Author information

Author/s: Manchia, Mirko (M); Congiu, Donatella (D); Squassina, Alessio (A); Lampus, Simona (S); Ardau, Raffaella (R); Chillotti, Caterina (C); Severino, Giovanni (G); Del Zompo, Maria (M);

Affiliation: Section of Clinical Pharmacology, Department of Neurosciences "B.B. Brodie", University of Cagliari, P.O. San Giovanni di Dio, Via Ospedale 46, 09124 Cagliari, Italy. mirkomanchia(-atsign-)tiscali.it

Journal and publication information

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal: Psychiatry research (Psychiatry Res), published in Ireland. (Language: eng)

Reference: 2009-Sep; vol 169 (issue 2) : pp 164-6

Dates: Created 2009/09/07; Completed 2009/10/29;

PMID: 19647327, status: MEDLINE (last retrieval date: 10/29/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Associated Chemicals: Antimanic Agents (0) ; Dopamine Plasma Membrane Transport Proteins (0) ; Lithium Compounds (0) ; Receptor, Serotonin, 5-HT2A (0) ; Receptors, Dopamine (0) ; Receptors, Dopamine D1 (0) ; Receptors, Dopamine D2 (0) ; Receptors, Dopamine D3 (0) ; SLC6A4 protein, human (0) ; Serotonin Plasma Membrane Transport Proteins (0)

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