Long-term evaluation of collagen and elastin following infrared (1100 to 1800 nm) irradiation.

Full Abstract

BACKGROUND: Infrared irradiation stimulates collagen production, but histological differences in its long-term effects on type I versus type III collagen and elastin in human tissue are unclear. OBJECTIVE: To investigate the effects of infrared irradiation. METHODS AND MATERIALS: In vivo human tissues in sun-protected and sun-exposed areas were irradiated with infrared. Histological samples were analyzed, and visual changes were assessed up to 90 days post-treatment. RESULTS: Infrared irradiation provided long-term increases in collagen and elastin levels on post-irradiation days 30, 60 and 90 compared to controls. Significant increases in type I collagen persisted until 30 and 60 days, and in sun-protected and exposed skin biopsies, respectively. Significant increases in type III collagen and elastin persisted until 90 days in both sun-protected and sun-exposed skin biopsies. CONCLUSION: Infrared irradiation provides safe and effective long-term stimulation of collagen I and III and elastin, which is beneficial for improving skin laxity and wrinkles.

Author information

Author/s: Tanaka, Yohei (Y); Matsuo, Kiyoshi (K); Yuzuriha, Shunsuke (S);

Affiliation: Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Matsumoto, Japan. yoheimd(-atsign-)yahoo.co.jp

Journal and publication information

Publication Type: Journal Article

Journal: Journal of drugs in dermatology : JDD (J Drugs Dermatol), published in United States. (Language: eng)

Reference: 2009-Aug; vol 8 (issue 8) : pp 708-12

Dates: Created 2009/08/11; Completed 2009/09/22;

PMID: 19663107, status: MEDLINE (last retrieval date: 9/22/2009, IMS Date: )

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