|
|
| Research article summary (published 9 Aug 2009): |
Tamoxifen: the drug that came in from the cold.
Full Abstract
Despite the perception of many oncologists that tamoxifen is an inferior drug, and should be substituted by an aromatase inhibitor in post-menopausal women, the current evidence strongly supports the view that AIs should be used 2-3 years after tamoxifen to achieve the maximal overall survival (OS) advantage.
Author information
Author/s: Hughes-Davies, L (L); Caldas, C (C); Wishart, G C (GC);
Affiliation: Cambridge Breast Unit, Addenbrooke's Hospital, Hills Road, Cambridge, UK.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal: British journal of cancer (Br J Cancer), published in England. (Language: eng)
Reference: 2009-Sep; vol 101 (issue 6) : pp 875-8
Dates: Created 2009/09/09; Completed 2009/09/23; Revised 2009/10/28;
PMID: 19672259, status: MEDLINE (last retrieval date: 10/29/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
These are the highest related articles currently in the database:
- Optimizing endocrine therapy for breast cancer.
8 Mar 2005 - The role of aromatase inhibitor (AI) in the treatment of breast cancer.
30 Dec 2004 - A new day dawns: women without oestrogen or is a balance best?
8 Sep 2002 - Current controversies in the endocrine therapy of advanced breast cancer.
30 Dec 1991 - Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer.
30 Dec 2004 - Neoadjuvant tamoxifen for hormone-sensitive non-metastatic breast carcinomas in early postmenopausal women.
30 Jan 2002 - [Tamoxifen and aromatase inhibitors in the treatment of breast cancer in menopausal women: pharmacological and clinical aspects]
29 Nov 2004 - [Antiestrogen treatment in postmenopausal patients with metastatic breast cancer]
8 Sep 2007 - New stars in the sky of treatment for early breast cancer.
9 Mar 2004 - Different survival determinants of metastatic breast cancer patients treated with endocrine therapy or chemo-endocrine therapy.
30 Mar 1998
Related Article Map
Legend:
- FREE Full text Article.
- Abstract only.
- Title only. More help.
See a large map of 100+ related articles.