Research article summary (published 13 Aug 2009):

Muscle inhibition following tendon stimulation is reduced in chronic stroke.

Full Abstract

OBJECTIVE: Electrical tendon stimulation elicits reflex inhibition in the homonymous muscle that is thought to be mediated by group III afferents. The study goals were to: evaluate group III-mediated reflex inhibition in people with post-stroke hemiparesis; determine the presence of heteronymous group III pathways; investigate the relevance of reflex inhibition to arm function. METHODS: Reflex responses were recorded in wrist, elbow, and shoulder muscles following stimulation of the extensor carpi radialis (ECR) tendon in 16 people with post-stroke hemiparesis and 16 control subjects. In control subjects, reflex inhibition also was compared between static and dynamic muscle activation. RESULTS: Reflex inhibition following ECR tendon stimulation was present in heteronymous muscles of most, but not all, stroke and control subjects. The level of reflex inhibition was significantly reduced in stroke subjects. In the controls, reflex inhibition was greater during dynamic activation of elbow muscles compared to static activation. CONCLUSIONS: Evidence that reflex inhibition projects to heteronymous muscles and is modulated during movement suggests a role for the reflex in multi-joint coordination. The reflex is impaired in post-stroke hemiparesis. SIGNIFICANCE: Abnormalities in the regulation of group III-mediated muscle inhibition in the stroke population may contribute to impaired muscle activation patterns during movement.

Author information

Author/s: Lewis, Gwyn N (GN); McNair, Peter J (PJ);

Affiliation: Health and Rehabilitation Research Centre, AUT University, New Zealand. gwyn.lewis(-atsign-)aut.ac.nz

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology (Clin Neurophysiol), published in Netherlands. (Language: eng)

Reference: 2009-Sep; vol 120 (issue 9) : pp 1732-40

Dates: Created 2009/09/08; Completed 2009/09/23;

PMID: 19683961, status: MEDLINE (last retrieval date: 9/23/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Aged Aged, 80 and over Chronic Disease Data Interpretation, Statistical Electric Stimulation Electromyography Female Humans

Humans Male Middle Aged Muscle Contraction - physiology Muscle, Skeletal - physiology Paresis - physiopathology Reflex, Stretch - physiology Stroke - physiopathology Tendons - physiology

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