Research article summary (published 30 Aug 2009):

A Golgi-on-a-chip for glycan synthesis.

Full Abstract

One of the primary functions of the Golgi apparatus is the assembly of glycans on macromolecules destined for secretion or the plasma membrane. A recent study describes the first step toward an artificial Golgi, based on a microfluidic chip and magnetic nanoparticles.

Author information

Author/s: Xu, Ding (D); Esko, Jeffrey D (JD);

Affiliation: Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California-San Diego, La Jolla, California, USA.

Journal and publication information

Publication Type: Journal Article

Journal: Nature chemical biology (Nat Chem Biol), published in United States. (Language: eng)

Reference: 2009-Sep; vol 5 (issue 9) : pp 612-3

Dates: Created 2009/08/19; Completed 2009/09/16;

PMID: 19690535, status: MEDLINE (last retrieval date: 9/16/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Binding Sites Glycosylation Golgi Apparatus - enzymology; metabolism Heparitin Sulfate - biosynthesis; chemistry

Ligands Microfluidic Analytical Techniques Models, Biological Polysaccharides - biosynthesis; chemistry

Associated Chemicals: Ligands (0) ; Polysaccharides (0) ; Heparitin Sulfate (9050-30-0)

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