Research article summary (published 29 Sep 2009):

Recurrent, multifocal Mycobacterium avium-intercellulare infection in a patient with interferon-gamma autoantibody.

Full Abstract

We describe a patient who experienced severe osteomyelitis because of Mycobacterium avium-intercellulare infection and high-titered autoantibodies against interferon-gamma. In addition to antimycobacterial chemotherapy, we treated our patient with plasmapheresis and cyclophosphamide. The treatment induced a remission after 3 years of follow-up.

Author information

Author/s: Baerlecken, N (N); Jacobs, R (R); Stoll, M (M); Schmidt, R E (RE); Witte, T (T);

Affiliation: Clinic for Immunology and Rheumatology, Medical School of Hanover, Carl-Neuberg-Str 1, 30625 Hanover, Germany. baerlecken.niklas(-atsign-)mh-hannover.de

Journal and publication information

Publication Type: Case Reports; Journal Article

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (Clin Infect Dis), published in United States. (Language: eng)

Reference: 2009-Oct; vol 49 (issue 7) : pp e76-8

Dates: Created 2009/09/10; Completed 2009/11/02;

PMID: 19725781, status: MEDLINE (last retrieval date: 11/2/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Antitubercular Agents - therapeutic use Autoantibodies - blood Autoimmune Diseases - complications Cyclophosphamide - therapeutic use Female Humans

Immunosuppressive Agents - therapeutic use Interferon-gamma - immunology Mycobacterium Infections - drug therapy; microbiology; therapy Mycobacterium avium - isolation & purification Osteomyelitis - microbiology Plasmapheresis Recurrence

Associated Chemicals: Antitubercular Agents (0) ; Autoantibodies (0) ; Immunosuppressive Agents (0) ; Cyclophosphamide (50-18-0) ; Interferon-gamma (82115-62-6)

Related articles

These are the highest related articles currently in the database:

• Improved detection times for Mycobacterium avium complex and Mycobacterium tuberculosis with the BACTEC radiometric system. 30 Oct 1985
• Pulmonary Mycobacterium avium infection in an immunocompetent aged woman related to use of home bath with a circulating water system. 29 Nov 2002
• Agranulocytosis in a patient with primary Sjögren's syndrome. 29 Nov 1990
• Otomastoiditis caused by Mycobacterium avium-intracellulare. 30 Oct 1986
• Status of mycobacterial infections of the lungs. 27 Feb 1973
• Mycobacterium avium-intracellulare: a cause of disseminated life-threatening infection in homosexuals and drug abusers. 29 Sep 1982
• [Mycobacteriosis of the lung due to M. avium] 29 Jun 1975
• Acid-fast smear and culture of respiratory secretions, bone marrow, and stools as predictors of disseminated Mycobacterium avium complex infection. 29 Apr 1987
• Sources of Mycobacterium avium complex infection resulting in human diseases. 29 Nov 1977
• [Generalized mycobacterium avium infection in an infant (author's transl)] 29 Apr 1975

See 100+ related articles.

Related Article Map

Legend: - FREE Full text Article. - Abstract only. - Title only. More help.

See a large map of 100+ related articles.