Intrathecal baclofen use in adults with cerebral palsy.

Full Abstract

Intrathecal baclofen (ITB) is an effective treatment for both spasticity and dystonia in people with cerebral palsy (CP). Its use is becoming increasingly common. ITB is typically associated with fewer side effects than the oral form of the product, but there are risks related to the hardware needed for intrathecal delivery. Much of what has been reported in the literature about ITB is based on experience with children or groups of children and adults; few reports exclusively address its use in adults with CP. These reports indicate that muscle tone is consistently reduced, but there is some variability in functional outcomes. Few well-controlled studies have been done. Controversies remain concerning ITB, including whether a trial is needed before pump implantation, proper catheter tip placement, and programming options, as well as whether it contributes to the development or progression of scoliosis. These and other unanswered questions should be addressed in a systematic way.

Author information

Author/s: Krach, Linda E (LE);

Affiliation: Department of Physical Medicine and Rehabilitation, University of Minnesota, Minneapolis, 55455, USA. krach002(-atsign-)umn.edu

Journal and publication information

Publication Type: Journal Article; Review

Journal: Developmental medicine and child neurology (Dev Med Child Neurol), published in England. (Language: eng)

Reference: 2009-Oct; vol 51 Suppl 4 (issue ) : pp 106-12

Dates: Created 2009/09/10; Completed 2009/10/06;

PMID: 19740217, status: MEDLINE (last retrieval date: 10/6/2009, IMS Date: )

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