Research article summary (published 29 Sep 2009):

Behaviorally measured audiograms and gap detection thresholds in CBA/CaJ mice.

Full Abstract

Tone detection and temporal gap detection thresholds were determined in CBA/CaJ mice using a Go/No-go procedure and the psychophysical method of constant stimuli. In the first experiment, audiograms were constructed for five CBA/CaJ mice. Thresholds were obtained for eight pure tones ranging in frequency from 1 to 42 kHz. Audiograms showed peak sensitivity between 8 and 24 kHz, with higher thresholds at lower and higher frequencies. In the second experiment, thresholds for gap detection in broadband and narrowband noise bursts were measured at several sensation levels. For broadband noise, gap thresholds were between 1 and 2 ms, except at very low sensation levels, where thresholds increased significantly. Gap thresholds also increased significantly for low pass-filtered noise bursts with a cutoff frequency below 18 kHz. Our experiments revised absolute auditory thresholds in the CBA/CaJ mouse strain and demonstrated excellent gap detection ability in the mouse. These results add to the baseline behavioral data from normal-hearing mice which have become increasingly important for assessing auditory abilities in genetically altered mice.

Author information

Author/s: Radziwon, Kelly E (KE); June, Kristie M (KM); Stolzberg, Daniel J (DJ); Xu-Friedman, Matthew A (MA); Salvi, Richard J (RJ); Dent, Micheal L (ML);

Affiliation: Department of Psychology, University at BuValo, The State University of New York, BuValo, NY 14260, USA.

Grants: DC009483 (Agency:NIDCD NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology (J Comp Physiol A Neuroethol Sens Neural Behav Physiol), published in Germany. (Language: eng)

Reference: 2009-Oct; vol 195 (issue 10) : pp 961-9

Dates: Created 2009/09/28; Completed 2009/10/15;

PMID: 19756650, status: MEDLINE (last retrieval date: 10/15/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Acoustic Stimulation Animals Audiometry, Pure-Tone Auditory Threshold Behavior, Animal Conditioning, Operant Cues Discrimination (Psychology) Female

Female Male Mice Mice, Inbred CBA Motor Activity Pattern Recognition, Physiological Pitch Discrimination Sound Spectrography Time Perception

Related articles

These are the highest related articles currently in the database:

• Second-order modulation detection thresholds for pure-tone and narrow-band noise carriers. 30 Oct 2001
• Behavioral model of chronic tinnitus in rats. 29 Sep 1999
• Stimulus control of heart rate by auditory frequency and auditory pattern in pigeons. 27 Feb 1974
• Detection and discrimination of simple and complex sounds by hearing-impaired Belgian Waterslager canaries. 29 Nov 2007
• Relative pitch perception in Japanese monkeys (Macaca fuscata). 30 May 2001
• Sound segregation based on temporal envelope structure and binaural cues. 30 Jul 2008
• Frequency selectivity in the parakeet (Melopsittacus undulatus) studied with psychophysical tuning curves. 30 May 1978
• Age-related changes in within- and between-channel gap detection using sinusoidal stimuli. 30 Mar 2006
• Two-tone suppression in the cricket, Eunemobius carolinus (Gryllidae, Nemobiinae). 27 Feb 2002
• Flight and hearing: ultrasound sensitivity differs between flight-capable and flight-incapable morphs of a wing-dimorphic cricket species. 30 Aug 2007

See 100+ related articles.

Related Article Map

Legend: - FREE Full text Article. - Abstract only. - Title only. More help.

See a large map of 100+ related articles.