Multispectral fluorescence imaging.

Full Abstract

Multispectral fluorescence imaging (MSFI) is a rapidly growing field with broad applications in both preclinical and clinical settings. Application of this novel technology in small-animal imaging and microscopy produces enhanced sensitivity and reliable quantification and resolves multiple simultaneous signals. MSFI flow cytometry can quantify multiple fluorescent parameters with morphologic or subcellular spatial details on millions of cells. MSFI has the potential to improve the accuracy of disease detection or differentiation and intrasurgical metastatic diagnosis, guide neurosurgeries, and monitor treatment response.

Author information

Author/s: Zhou, Lanlan (L); El-Deiry, Wafik S (WS);

Affiliation: Department of Bioengineering, University of Pennsylvania School of Engineering and Applied Science, Philadelphia, Pennsylvania, USA.

Journal and publication information

Publication Type: Journal Article; Review

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine (J Nucl Med), published in United States. (Language: eng)

Reference: 2009-Oct; vol 50 (issue 10) : pp 1563-6

Dates: Created 2009/10/01; Completed 2009/11/03;

PMID: 19759119, status: MEDLINE (last retrieval date: 11/3/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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