[Proton magnetic resonance spectroscopic imaging and other types of metabolic imaging for radiotherapy planning in adult and pediatric high-grade gliomas]

(Apport de l'imagerie de spectroscopie de résonance magnétique du proton et des autres imageries métaboliques à la définition des volumes cibles de radiothérapie des tumeurs gliales de l'adulte et de l'enfant.)

Full Abstract

Radiation therapy improves survival in high-grade gliomas but most patients relapse and usually within radiation fields. This may be due to uncertainties in target delineation and difficulties in identifying radioresistant regions for dose escalation. The use of T1 and T2-weighted magnetic resonance imaging (MRI) coregistration on the planning CT improves the target volume definition but magnetic resonance spectroscopic imaging (MRSI) and other types of metabolic and functional imaging (perfusion MRI, diffusion-weighted MRI, positron emission tomography (PET) imaging) may give useful additional information for target delineation. This article focuses on the potential of each imaging modality: assessment of response to treatment, detection of abnormalities not seen on MRI, predictive value for the site of local relapse. The incorporation of such techniques may improve target volume definition.

Author information

Author/s: Laprie, A (A);

Affiliation: Département de Radiothérapie, Institut Claudius-Regaud, 31052 Toulouse cedex, France. laprie.anne(-atsign-)claudiusregaud.fr

Journal and publication information

Publication Type: English Abstract; Journal Article; Review

Journal: Cancer radiothérapie : journal de la Société française de radiothérapie oncologique (Cancer Radiother), published in France. (Language: fre)

Reference: 2009-Oct; vol 13 (issue 6-7) : pp 556-61

Dates: Created 2009/10/09; Completed 2009/11/02;

PMID: 19766525, status: MEDLINE (last retrieval date: 11/2/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.