Research article summary (published 30 Aug 2009):

Evaluation of automated stir bar sorptive extraction-thermal desorption-gas chromatography electron capture negative ion mass spectrometry for the analysis of PBDEs and PBBs in sheep and human serum.

Full Abstract

Stir-bar sorptive extraction and automated thermal desorption/cryotrapping interfaced to capillary gas chromatography and electron capture negative ion mass spectrometry is shown to effectively isolate and recover polybrominated diphenyl ethers and polybrominated biphenyls from sheep and human serum. This paper describes the development of the method and demonstrates the feasibility of using Twister with spiked serum. Conditions for conducting stir-bar sorptive extraction and for automated thermal desorption that led to acceptable analyte recoveries were optimized. The approach to sample preparation introduced here significantly reduces tedious labor and solvent consumption associated with conventional liquid-liquid extraction.

Author information

Author/s: Loconto, Paul R (PR);

Affiliation: Division of Chemistry and Toxicology, Bureau of Laboratories, Michigan Department of Community Health, Lansing, Michigan 48909, USA.

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal: Journal of chromatographic science (J Chromatogr Sci), published in United States. (Language: eng)

Reference: 2009-Sep; vol 47 (issue 8) : pp 656-69

Dates: Created 2009/09/23; Completed 2009/10/27;

PMID: 19772742, status: MEDLINE (last retrieval date: 10/27/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Gas Chromatography-Mass Spectrometry - methods Halogenated Diphenyl Ethers - blood Humans

Humans Polybrominated Biphenyls - blood Reproducibility of Results Sheep

Associated Chemicals: Halogenated Diphenyl Ethers (0) ; Polybrominated Biphenyls (0)

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