 |
| Research article summary (published 30 Aug 2009): |
Simultaneous determination of seven components in Qibaomeiran pill by HPLC-DAD.
Full Abstract
A high-performance liquid chromatography coupled with photo diode array detection method is developed for simultaneous determination of seven active components in Qibaomeiran pill, including rutin, 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glycoside, ferulic acid, psoralen, isopsoralen, emodin, and physcion. The analysis is performed on a C(18) column using a mobile phase composed of A (0.1% acetic acid) and B (acetonitrile) with linear gradient elution. Four wavelengths at 245, 290, 320, and 350 nm were chosen as the monitoring wavelength to determine seven active components, respectively. All the compounds show good linearity (r > 0.999). The developed method is fully validated in respect to precision, repeatability, and accuracy. The proposed method is successfully applied to quantify the seven active components in different Qibaomeiran pill samples. The results indicate that the developed assay could be considered as a suitable quality control method for the Qibaomeiran pill.
Author information
Author/s: Wang, Chunying (C); Wang, Qiao (Q); Yuan, Zhifang (Z); Yang, Wei (W); Xie, Fengli (F); Zhang, Lantong (L);
Affiliation: Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, 050017, PR China.
Journal and publication information
Publication Type: Journal Article
Journal: Journal of chromatographic science (J Chromatogr Sci), published in United States. (Language: eng)
Reference: 2009-Sep; vol 47 (issue 8) : pp 723-7
Dates: Created 2009/09/23; Completed 2009/10/27;
PMID: 19772753, status: MEDLINE (last retrieval date: 10/27/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
Related articles
These are the highest related articles currently in the database:
- Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography.
13 Jun 2005 - [Chemical constituents of roots, rhizomes and stems of Amomum villosum Lour] 29 Nov 1994
- [Simultaneous determination of 4 anthraquinones in Kuhuang injection by RP-HPLC] 30 Oct 2004
- [Simultaneous determination of resveratrol, emodin, chrysophanol, physcion, in root of Polygonam cuspidatum and its extract by HPLC] 30 Jan 2006
- [Effect of preparation on the major chemical constituents of Polygonum multiflorum] 29 Sep 2006
- Microbial glycosylation of four free anthraquinones by Absidia coerulea. 30 Dec 2003
- Screening and analysis of an antineoplastic compound in Rhizoma Chuanxiong by means of in vitro metabolism and HPLC-MS. 24 Jul 2006
- [Chromatographic identification of a compound similar to ferulic acid in the decoction of Herb Leonuri] 29 Sep 2002
- [Determination of emodin in caulis Polygoni multiflori and huangshen infusion by TLC-scanning]
29 Apr 1994 - [Determination of emodin in kangnaoshuai capsules and in radix Polygoni multifori by thin layer chromatography scanning] 30 Dec 1996
Related Article Map
4/29/1994
9/29/2006
Higher Relevance Score (100)
Lower Relevance Score (82)
Legend: 
- FREE Full text Article. - Abstract only. - Title only. More help.
See a large map of 100+ related articles.