Cortical enlightenment: are attentional gamma oscillations driven by ING or PING?

Full Abstract

The response of a neuron to sensory stimuli can only give correlational support for functional hypotheses. To experimentally test causal function, the neural activity needs to be manipulated in a cell-type-specific as well as spatially and temporally precise way. We review recent optogenetic experiments on parvalbumin-positive cortical interneurons that link modeling studies of synchronization to experimental studies on attentional modulation of gamma oscillations in primates.

Author information

Author/s: Tiesinga, Paul (P); Sejnowski, Terrence J (TJ);

Affiliation: Donders Centre for Neuroscience, Radboud University Nijmegen, Nijmegen, The Netherlands.

Grants: (Agency:Howard Hughes Medical Institute)

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal: Neuron (Neuron), published in United States. (Language: eng)

Reference: 2009-Sep; vol 63 (issue 6) : pp 727-32

Dates: Created 2009/09/25; Completed 2009/10/09;

PMID: 19778503, status: MEDLINE (last retrieval date: 10/9/2009, IMS Date: )

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