Research article summary (published 30 Aug 2009):

Endoscopic cyclophotocoagulation for the treatment of glaucoma: an Asian experience.

Full Abstract

BACKGROUND: To describe the efficacy and safety of endoscopic cyclophotocoagulation in Asian patients with glaucoma. METHODS: Retrospective case series. Consecutive cases of endoscopic cyclophotocoagulation performed by one surgeon during the study period were included. Patients' records were reviewed for clinical and demographic factors, treatments, intraocular pressure (IOP), visual acuity and any complications. RESULTS: Twenty-nine eyes of 29 patients were treated. Their mean age was 73.6 +/- 9.4 years. The mean follow-up duration was 15.9 +/- 8.9 months. Eleven patients had primary open-angle glaucoma, two normal tension glaucoma, six chronic angle-closure glaucoma, five neovascular glaucoma, four secondary open-angle glaucoma and one secondary angle-closure glaucoma. Twenty patients had endoscopic cyclophotocoagulation combined with cataract surgery. Mean pretreatment IOP was 21.8 +/- 6.6 mmHg. Mean post-treatment IOP at 18 months (n = 17) was 16.2 +/- 4.1 mmHg (P = 0.02) and 17.9 +/- 4.9 mmHg (P = 0.18) at 24 months (n = 10). The mean number of anti-glaucoma medications pretreatment was reduced from 2.0 +/- 1.0 to 0.9 +/- 0.9 at 18 months post-treatment (P = 0.04) and 1.2 +/- 0.8 at 24 months (P = 0.13). The overall success rate based on IOP reduction of 20% or greater at last follow-up was 48.3%. Visual acuity was reduced in five eyes. Complications included one case each of hyphaema, bullous keratopathy, transient pigment dispersion and iris burn. CONCLUSION: Endoscopic cyclophotocoagulation may have a treatment role in Asian patients with glaucoma. The success rate appears poorer than previously reported in Caucasian populations. The treatment effect appeared to wane between 18 and 24 months post-treatment.

Author information

Author/s: Yip, Leonard W (LW); Yong, Shao O (SO); Earnest, Arul (A); Ji, Jian (J); Lim, Boon A (BA);

Affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore. leonard_yip(-atsign-)ttsh.com.sg

Journal and publication information

Publication Type: Journal Article

Journal: Clinical & experimental ophthalmology (Clin Experiment Ophthalmol), published in Australia. (Language: eng)

Reference: 2009-Sep; vol 37 (issue 7) : pp 692-7

Dates: Created 2009/09/30; Completed 2009/10/28;

PMID: 19788666, status: MEDLINE (last retrieval date: 10/28/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Aged Aged, 80 and over Antihypertensive Agents - administration & dosage Ciliary Body - surgery Endoscopy Female Follow-Up Studies Glaucoma, Angle-Closure - ethnology; physiopathology; surgery Glaucoma, Neovascular - ethnology; physiopathology; surgery Glaucoma, Open-Angle - ethnology; physiopathology; surgery Humans

Humans Intraocular Pressure - physiology Intraoperative Complications Laser Coagulation Male Middle Aged Postoperative Complications Retrospective Studies Singapore - epidemiology Treatment Outcome Visual Acuity - physiology

Associated Chemicals: Antihypertensive Agents (0)

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