Research article summary (published 30 Sep 2009):

It's all about timing.

Full Abstract

In the formation of long-term memories, a "spaced" distribution of study sessions is more beneficial than closely spaced "massed" study sessions. Pagani et al. (2009) examine the molecular basis of this spacing effect in Drosophila and find a role for the SHP2 homolog, corkscrew, an activator of Ras/MAPK signaling, in establishing optimal spacing intervals.

Author information

Author/s: Philips, Gary T (GT); Carew, Thomas J (TJ);

Affiliation: Department of Neurobiology and Behavior and the Center for the Neurobiology of Learning and Memory, University of California-Irvine, Irvine, CA 92607-4450, USA.

Journal and publication information

Publication Type: Comment; Journal Article

Journal: Cell (Cell), published in United States. (Language: eng)

Reference: 2009-Oct; vol 139 (issue 1) : pp 23-5

Dates: Created 2009/10/06; Completed 2009/10/27;

PMID: 19804749, status: MEDLINE (last retrieval date: 10/27/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

CommentOn: Cell. 2009 Oct 2;139(1):186-98. (PMID: 19804763)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Drosophila Proteins - metabolism Humans Learning

Learning MAP Kinase Signaling System Memory Protein Tyrosine Phosphatases, Non-Receptor - metabolism

Associated Chemicals: Drosophila Proteins (0) ; Protein Tyrosine Phosphatases, Non-Receptor (EC 3.1.3.48) ; corkscrew protein, Drosophila (EC 3.1.3.48)

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