Research article summary (published 4 Oct 2009):

Prognosis for patients with chronic low back pain: inception cohort study.

Full Abstract

OBJECTIVES: To describe the course of chronic low back pain in an inception cohort and to identify prognostic markers at the onset of chronicity. DESIGN: Inception cohort study with one year follow-up. SETTING: Primary care clinics in Sydney, Australia. PARTICIPANTS: The study sample was a subcohort of an inception cohort of 973 consecutive patients presenting to primary care with acute low back pain (<2 weeks' duration). 406 participants whose pain persisted for three months formed the inception cohort of patients with chronic low back pain. MAIN OUTCOME MEASURES: Outcomes and putative predictors measured at initial presentation, onset of chronicity (study entry), and follow-up at nine and 12 months. Recovery was determined from measures of pain intensity, disability, and work status. The association between potential prognostic factors and time to recovery was modelled with Cox regression. RESULTS: Completeness of follow-up was 97% of total person time for all outcomes. The cumulative probability of being pain-free was 35% at nine months and 42% at 12 months and for complete recovery was 35% at nine months and 41% at 12 months. Of the 259 participants who had not recovered from pain related disability at entry to the chronic study, 47% had recovered by 12 months. Previous sick leave due to low back pain, high disability levels or high pain intensity at onset of chronicity, low levels of education, greater perceived risk of persistent pain, and being born outside Australia were associated with delayed recovery. CONCLUSION: More than one third of patients with recent onset, non-radicular chronic low back pain recover within 12 months. The prognosis is less favourable for those who have taken previous sick leave for low back pain, have high disability levels or high pain intensity at onset of chronic low back pain, have lower education, perceive themselves as having a high risk of persistent pain, and were born outside Australia.

Author information

Author/s: Costa, Luciola da C Menezes (Lda C); Maher, Christopher G (CG); McAuley, James H (JH); Hancock, Mark J (MJ); Herbert, Robert D (RD); Refshauge, Kathryn M (KM); Henschke, Nicholas (N);

Affiliation: George Institute for International Health, University of Sydney. lmenezes(-atsign-)george.org.au

Journal and publication information

Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal: BMJ (Clinical research ed.) (BMJ), published in England. (Language: eng)

Reference: 2009-; vol 339 (issue ) : pp b3829

Dates: Created 2009/10/07; Completed 2009/10/28;

PMID: 19808766, status: MEDLINE (last retrieval date: 10/28/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

CommentIn: BMJ. 2009;339:b3694. (PMID: 19808764)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Attitude to Health Chronic Disease Cohort Studies Disabled Persons - statistics & numerical data Educational Status Female Humans

Low Back Pain - diagnosis; ethnology Male Middle Aged New South Wales Primary Health Care - statistics & numerical data Prognosis Risk Factors Sick Leave - statistics & numerical data

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