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Research article summary (published 30 Aug 2009):

The effects of a commercially available weight loss program among obese patients with type 2 diabetes: a randomized study.

Full Abstract

The purpose of this study was to assess the effects of a commercially available weight loss program on weight and glycemic control among obese patients with type 2 diabetes. Participants included 69 patients (49 females, 20 males) with type 2 diabetes who had a mean +/- SD age of 52.2 +/- 9.5 years, a body mass index of 39.0 +/- 6.2 kg/m(2), and hemoglobin A1c (HbA1c) of 7.5 +/- 1.6%. Over half (52.2%) of the participants were African American. Participants were randomly assigned to: 1) a portion-controlled diet (NutriSystem D) (PCD) or 2) a diabetes support and education (DSE) program. After the initial 3 months, the PCD group continued on the PCD for the remaining 3 months, and the DSE group crossed over to PCD for the remaining 3 months. The primary comparison for this study was at 3 months. At 3 months, the PCD group lost significantly more weight (7.1 +/- 4%) than the DSE group (0.4 +/- 2.3%) (P < 0.0001). From 3 to 6 months the change in weight for both groups was statistically significant. After 3 months, the PCD group had greater reductions in HbA1c than the DSE group (-0.88 +/- 1.1 vs 0.03 +/- 1.09; P < 0.001). From 3 to 6 months the PCD group had no further change in HbA1c, while the DSE group showed a significant reduction. These data suggest that obese patients with type 2 diabetes will experience significant improvements in weight, glycemic control, and cardiovascular disease risk factors after the use of a commercially available weight management program.

 

Author information

Author/s: Foster, Gary D (GD); Borradaile, Kelley E (KE); Vander Veur, Stephanie S (SS); Leh Shantz, Kerri (K); Dilks, Rebecca J (RJ); Goldbacher, Edie M (EM); Oliver, Tracy L (TL); Lagrotte, Caitlin A (CA); Homko, Carol (C); Satz, Wayne (W);

Affiliation: Center for Obesity Research and Education, Temple University, Philadelphia, PA 19140, USA. gfoster(-atsign-)temple.edu

Journal and publication information

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal: Postgraduate medicine (Postgrad Med), published in United States. (Language: eng)

Reference: 2009-Sep; vol 121 (issue 5) : pp 113-8

Dates: Created 2009/10/12; Completed 2009/11/04;

PMID: 19820280, status: MEDLINE (last retrieval date: 11/4/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Associated Chemicals: Hemoglobin A, Glycosylated (0) ; Triglycerides (0) ; hemoglobin A1c protein, human (0) ; Cholesterol (57-88-5)

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