Treatment of bipolar disorders and metabolic syndrome: implications for primary care.

Full Abstract

Recognition of the prevalence of mood disorders and increased availability of medication options have led to calls for treating bipolar disorders in the primary care setting. Second-generation antipsychotic medications (SGAs) were initially lauded for treating bipolar disorders because of their efficacy and perceived safety relative to first-generation antipsychotic medications. Metabolic syndrome is a constellation of risk factors for cardiovascular disease and type 2 diabetes mellitus, which may emerge when treating bipolar disorders with SGAs. We conducted a search of the research literature examining the association between different SGAs and metabolic syndrome. Based on our review, we offer guidelines for monitoring patient status regarding metabolic syndrome and for providing interventions to promote healthy diet and exercise.

Author information

Author/s: Bell, Paul F (PF); McKenna, James P (JP); Roscoe, Brandon M (BM);

Affiliation: Heritage Valley Health System, Beaver Falls, PA 15010, USA. pbell(-atsign-)hvhs.org

Journal and publication information

Publication Type: Journal Article; Review

Journal: Postgraduate medicine (Postgrad Med), published in United States. (Language: eng)

Reference: 2009-Sep; vol 121 (issue 5) : pp 140-4

Dates: Created 2009/10/12; Completed 2009/11/04;

PMID: 19820282, status: MEDLINE (last retrieval date: 11/4/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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