Trends in the epidemiology of human G1P[8] rotaviruses: a hungarian study.

Full Abstract

Epidemiological trends of the globally most common rotavirus genotype, G1P[8], were investigated in Hungary during a 16-year period by sequencing and phylogenetic analysis of the surface antigens. Antigen shift among epidemiologically major G1P[8] strains was observed in 6 seasons, as indicated by changes in the sublineages of the G1 VP7 and the P[8] VP4 genes. The temporal clustering of some rotavirus VP4 and VP7 gene sublineages and the periodic emergence and/or resurgence of previously unrecognized rotavirus sublineages in the study population suggest a dynamic nature for these common strains. Recently established international strain surveillance networks may help to identify and track the spread of epidemiologically important rotavirus strains across countries and continents.

Author information

Author/s: Bányai, Krisztián (K); Gentsch, Jon R (JR); Martella, Vito (V); Bogdán, Agnes (A); Havasi, Viktória (V); Kisfali, Péter (P); Szabó, Alíz (A); Mihály, Ilona (I); Molnár, Péter (P); Melegh, Béla (B); Szücs, György (G);

Affiliation: Regional Laboratory of Virology, Baranya County Institute of State Public Health Service, Hungarian Academy of Sciences, Budapest, Hungary. bkrota(-atsign-)hotmail.com

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: The Journal of infectious diseases (J Infect Dis), published in United States. (Language: eng)

Reference: 2009-Nov; vol 200 Suppl 1 (issue ) : pp S222-7

Dates: Created 2009/10/13; Completed 2009/11/03;

PMID: 19821713, status: MEDLINE (last retrieval date: 11/3/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.