MHC class I: an unexpected role in neuronal plasticity.

Full Abstract

For the nervous system to translate experience into memory and behavior, lasting structural change at synapses must occur. This requirement is clearly evident during critical periods of activity-dependent neural development, and accumulating evidence has established a surprising role for the major histocompatibility complex class I (MHCI) proteins in this process.

Author information

Author/s: Shatz, Carla J (CJ);

Affiliation: Bio-X and Departments of Biology and Neurobiology, James H. Clark Center, 318 Campus Drive W1.1, Stanford University, Stanford CA 94305-5437, USA. cshatz(-atsign-)stanford.edu

Grants: R01 EY02858 (Agency:NEI NIH HHS) ; R01 MH071666 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal: Neuron (Neuron), published in United States. (Language: eng)

Reference: 2009-Oct; vol 64 (issue 1) : pp 40-5

Dates: Created 2009/10/20; Completed 2009/11/05; Revised 2009/11/06;

PMID: 19840547, status: MEDLINE (last retrieval date: 11/9/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.