Cutaneous drug reactions.

Full Abstract

Cutaneous drug reactions are among the most common causes of skin eruptions in hospitalized patients. In outpatient clinics, drug eruptions represent a diagnostic and therapeutic challenge to the physician as any drug can cause an adverse cutaneous reaction. These reactions may be mediated by immunologic or nonimmunologic mechanisms. Cutaneous drug reactions may manifest themselves in various clinical morphologic patterns. Factors such as sun-exposure, concomitant drugs or diseases and host immune status can influence the type and morphology of lesions. History taking is one of the most important aspects in the evaluation of these patients and must be oriented so as to provide the information that will lead to the final diagnosis.

Author information

Author/s: Rubianes, E I (EI); Martín, R F (RF); Picó, M (M); González, J R (JR);

Affiliation: Department of Dermatology, University of Puerto Rico, School of Medicine, San Juan 00936-5067.

Journal and publication information

Publication Type: Journal Article; Review

Journal: Boletín de la Asociación Médica de Puerto Rico (Bol Asoc Med P R), published in PUERTO RICO. (Language: eng)

Reference: 1990-Oct; vol 82 (issue 10) : pp 434-42

Dates: Created 1991/05/06; Completed 1991/05/06; Revised 2005/11/16;

PMID: 2150483, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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