Stenotic intimal thickening of the external iliac artery in competition cyclists.

Full Abstract

Twenty-three cases of an arterial disease that affects competition cyclists are reported. Patients complained of intermittent acute claudication appearing on one lower limb only at the time of a maximal strain while cycling. Doppler hemodynamic investigation on an ergometric bicycle revealed a collapse of the ankle systolic pressure. Arteriography showed a sinuous lengthening and moderate stenosis of the external iliac artery. Pathologic examination of the artery disclosed a stenotic intimal thickening due to moderately cellular loose connective tissue with a variable distribution of collagen and elastic fibers. The cells in the affected zone were readily labeled with anti-actin and anti-myosin antibodies, and electron microscopy revealed features of synthetic smooth muscle cells. The lesion observed differs from intimal fibrodysplasia and from artherosclerosis. Abnormal local hemodynamic conditions may lead to this type of lesion. Thus, stenotic intimal thickening of the external iliac artery appears to be a new arterial disease defined by clinical, arteriographic, and pathologic features.

Author information

Author/s: Rousselet, M C (MC); Saint-Andre, J P (JP); L'Hoste, P (P); Enon, B (B); Megret, A (A); Chevalier, J M (JM);

Affiliation: Laboratoire d'Anatomie Pathologique, Centre Hospitalier Régional, Angers, France.

Journal and publication information

Publication Type: Journal Article

Journal: Human pathology (Hum Pathol), published in UNITED STATES. (Language: eng)

Reference: 1990-May; vol 21 (issue 5) : pp 524-9

Dates: Created 1990/06/18; Completed 1990/06/18; Revised 2004/11/17;

PMID: 2338332, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.