Hippocampal cells have behavioral correlates during the performance of an auditory working memory task in the rat.

Full Abstract

Single unit activity was recorded from the rat hippocampal CA1 and CA3 subfields, dentate gyrus (DG), entorhinal cortex (EC), subicular complex (SB), motor cortex (MC), prefrontal cortex (PFC), and dorsomedial thalamus (DMT) during performance of a continuous non-matching-to-sample task. The rats made go and no-go responses to indicate whether the current tone was the same as (match) or different from (nonmatch) the preceding tone. About half of the units from the MC, CA1, CA3, and DG had motor correlates, increments of activity immediately prior to a go response. This suggests that those regions are involved in making a response. The CA1 and CA3 had more units with comparison-motor correlates, increases of activity prior to a correct go response on nonmatch trials. This pattern of activity suggests that the CA1 and CA3 are involved in a mnemonic process of comparison between retained and current stimuli in a nonspatial auditory task.

Author information

Author/s: Sakurai, Y (Y);

Affiliation: Department of Psychology, Toyama Medical and Pharmaceutical University, Japan.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Behavioral neuroscience (Behav Neurosci), published in UNITED STATES. (Language: eng)

Reference: 1990-Apr; vol 104 (issue 2) : pp 253-63

Dates: Created 1990/07/12; Completed 1990/07/12; Revised 2006/11/15;

PMID: 2346620, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.