Research article summary (published 29 Apr 1979):

Topical induction of delayed hypersensitivity in the bladder.

Full Abstract

Delayed hypersensitivity reactions have been elicited by topical application of dinitrofluorobenzene to the bladder mucosa of sensitized dogs and rats. The resultant animal models may be of value in assessing the role of topically induced delayed hypersensitivity in the attempted immunotherapy of bladder cancer.

Author information

Author/s: Burke, C (C); Kumar, V (V); Olsson, C A (CA);

Journal and publication information

Publication Type: Journal Article

Journal: Investigative urology (Invest Urol), published in UNITED STATES. (Language: eng)

Reference: 1979-May; vol 16 (issue 6) : pp 421-7

Dates: Created 1979/09/01; Completed 1979/09/01; Revised 2006/11/15;

PMID: 447475, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adjuvants, Immunologic Administration, Topical Animals Dinitrofluorobenzene - administration & dosage; immunology Dogs Drug Hypersensitivity - immunology; pathology Hypersensitivity, Delayed - immunology; pathology Immunotherapy

Immunotherapy Male Mucous Membrane - drug effects; pathology Neoplasm Recurrence, Local - therapy Nitrobenzenes - administration & dosage; immunology Rats Urinary Bladder - drug effects; pathology Urinary Bladder Neoplasms - immunology; therapy

Associated Chemicals: Adjuvants, Immunologic (0) ; Nitrobenzenes (0) ; Dinitrofluorobenzene (70-34-8)

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