Occupational asthma due to pepsin.

Full Abstract

A 30-year-old atopic worker exposed to pepsin powder, herb, and pollen extracts at work developed an increase in asthmatic symptoms. Monitoring of peak expiratory flow rate revealed more important fluctuations at work. Skin prick tests yielded a large immediate reaction to pepsin. Specific inhalation challenges confirmed the diagnosis; an intense early response was documented after exposure to pepsin. The pepsin IgE RAST was positive and selectively inhibited by pepsin.

Author information

Author/s: Cartier, A (A); Malo, J L (JL); Pineau, L (L); Dolovich, J (J);

Journal and publication information

Publication Type: Case Reports; Journal Article

Journal: The Journal of allergy and clinical immunology (J Allergy Clin Immunol), published in UNITED STATES. (Language: eng)

Reference: 1984-May; vol 73 (issue 5 Pt 1) : pp 574-7

Dates: Created 1984/06/11; Completed 1984/06/11; Revised 2004/11/17;

PMID: 6425388, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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