Research article summary (published 29 Jun 1995):

[Comparison of anxiety and pain in two procedures of hematopoietic stem cell collection: cytapheresis and bone marrow collection]

(Comparaison de l'anxiété et de la douleur au cours de deux procédures de recueil des cellules-souches hématopoïétiques: la cytaphérèse et le prélèvement de moelle osseuse.)

Full Abstract

The aim of this study was to compare anxiety, pain and discomfort of cancer patients submitted to two procedures of hematopoietic stem cells collection: peripheral blood stem cells collection (PBSCC) or bone marrow collection (BMC). Patients, randomized (July 1993-February 1994), in view of autograft, to receive the first procedure or the second one, completed self-administered questionnaires before, during and after the procedure. Anxiety was evaluated by State-Trait Anxiety Inventory. Pain was assessed using visual analogical scale (VAS) and McGill Pain questionnaire. Before the procedure, in comparison with PBSCC patients (n = 40), BMC patients (n = 25) experienced more State-anxiety due to the procedure approach (p < 0.01) and more trouble or inconvenience for having to come and stay at the hospital (p < 0.0001). During the procedure, pain related to BMC, as assessed by VAS, is significatively higher than pain induced by PBSCC, whichever the access used (p < 0.001). The McGill total score is twice as high for BMC patients than for patients submitted to PBSCC with femoral catheter (n = 19). The latter patients significatively reported more pain than patients without femoral catheter (n = 21). At the discharge from hospital, 32% of BMC patients judged the procedure quite difficult vs 5% of PBSCC patients (p < 0.05). These results explain a higher acceptability of the peripheral blood stem cells collection.

Author information

Author/s: Macquart-Moulin, G (G); Auquier, P (P); Le Corroller, A G (AG); Blache, J L (JL); Novakovitch, G (G); Blaise, D (D); Faucher, C (C); Viens, P (P); Maraninchi, D (D); Moatti, J P (JP);

Affiliation: Inserm U379, Marseille, France.

Journal and publication information

Publication Type: Clinical Trial; Comparative Study; English Abstract; Journal Article; Randomized Controlled Trial

Journal: Bulletin du cancer (Bull Cancer), published in FRANCE. (Language: fre)

Reference: 1995-Jul; vol 82 (issue 7) : pp 582-8

Dates: Created 1995/10/30; Completed 1995/10/30; Revised 2006/11/15;

PMID: 7549121, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Anxiety - etiology; psychology Bone Marrow Cytapheresis Female Hematopoietic Stem Cells Humans

Humans Male Middle Aged Pain Measurement Questionnaires Specimen Handling - methods Test Anxiety Scale

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