Research article summary (published 29 Apr 1995):

[Diabetes mellitus--an epidemiologic study of fertility, contraception and sterility]

(Diabetes mellitus--Epidemiologische Studie zu Fertilität, Kontrazeption und Sterilität.)

Full Abstract

MATERIAL AND METHODS: Data from 672 female patients with diabetes mellitus between 17 and 42 years of age were collected by questionnaire. Mean manifestation age was 19.9 years (min. 1, max. 38). RESULTS: 72.39% of the patients were treated with insulin; one third had successful pregnancies. Only one of ten diabetics delivered more than once after diabetes had become manifest. At the time of the study, 126 (19.1%) of the patients attempted pregnancy; about one-fifth of these for more than 2 years. Diabetes manifestation occurred significantly earlier in patients who did not achieve conception. Correlation between daily insulin dose and infertility was proved, whereas duration of diabetes had no significant influence on fertility. Habitual abortion was found in 0.62%, among nulliparous patients 1.64%, respectively. Contraception was performed in 64.2% (32.8% hormonal contraceptives, 18.6% IUD, 1.8% natural family planning, 11.0% tubal sterilisation or hysterectomy, 35.8% no contraception). 47% of the used oral contraceptives contained a reduced oestrogen dose (30 micrograms estradiol). In one third of the users, IUD were longer than 5 years in place. Tubal sterilisation was found in 69 (10.44%) of diabetic patients; in 51 cases before the age of 30 years. CONCLUSIONS: Contraceptive methods should be selected carefully. Diabetic patients unsuccessfully attempting pregnancy should be referred early to a centre for reproductive medicine.

Author information

Author/s: Briese, V (V); Müller, H (H);

Affiliation: Frauenklinik, Universität Rostock.

Journal and publication information

Publication Type: English Abstract; Journal Article

Journal: Geburtshilfe und Frauenheilkunde (Geburtshilfe Frauenheilkd), published in GERMANY. (Language: ger)

Reference: 1995-May; vol 55 (issue 5) : pp 270-4

Dates: Created 1995/08/11; Completed 1995/08/11; Revised 2006/11/15;

PMID: 7607384, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Abortion, Habitual - epidemiology; etiology Adolescent Adult Contraception Behavior Contraceptives, Oral, Hormonal - administration & dosage; adverse effects Diabetes Mellitus, Type 1 - diagnosis; drug therapy; epidemiology Dose-Response Relationship, Drug Female Health Knowledge, Attitudes, Practice

Health Knowledge, Attitudes, Practice Humans Infant, Newborn Infertility, Female - epidemiology; etiology Insulin - adverse effects; therapeutic use Parity Pregnancy Pregnancy in Diabetics - diagnosis; drug therapy; epidemiology Risk Factors

Associated Chemicals: Contraceptives, Oral, Hormonal (0) ; Insulin (11061-68-0)

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