Research article summary (published 29 Apr 1994):

Novel antitumor sesquiterpenoids in Achillea millefolium.

Full Abstract

Three new antitumor sesquiterpenoids, achimillic acids A, B and C, were isolated as methyl esters from Achillea millefolium and their structures were determined spectroscopically. The compounds were found to be active against mouse P-388 leukemia cells in vivo.

Author information

Author/s: Tozyo, T (T); Yoshimura, Y (Y); Sakurai, K (K); Uchida, N (N); Takeda, Y (Y); Nakai, H (H); Ishii, H (H);

Affiliation: Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.

Journal and publication information

Publication Type: Journal Article

Journal: Chemical & pharmaceutical bulletin (Chem Pharm Bull (Tokyo)), published in JAPAN. (Language: eng)

Reference: 1994-May; vol 42 (issue 5) : pp 1096-100

Dates: Created 1994/09/23; Completed 1994/09/23; Revised 2003/11/14;

PMID: 8069962, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Animals Antineoplastic Agents, Phytogenic - chemistry; isolation & purification; pharmacology Cell Division - drug effects Crystallography, X-Ray Leukemia P388 - pathology Magnetic Resonance Spectroscopy Male

Male Methylation Mice Plant Extracts - chemistry; pharmacology Plants, Medicinal - chemistry Sesquiterpenes - chemistry; isolation & purification; pharmacology Tumor Cells, Cultured

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Antineoplastic Agents, Phytogenic (0) ; Plant Extracts (0) ; Sesquiterpenes (0)

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