Research article summary (published 30 Mar 1993):

Gianturco self-expanding stent in the treatment of stenosis in dialysis access grafts.

Full Abstract

This study evaluated the effectiveness of the Gianturco endovascular stent in preserving graft patency following percutaneous transvenous angioplasty (PTVA) of stenotic lesions occurring at the graft-vein anastomosis in hemodialysis patients with polytetrafluoroethylene grafts. Fifty-eight patients having 50% or greater stenosis were randomly divided into a treatment group (N = 28) and a concurrent control group (N = 30) following PTVA. In the treatment group, a stent was placed following dilatation. Graft thrombosis, the need for surgical revision, or the need for a repeat PTVA were used as end point events. The period of time from the PTVA/stent procedure to the end point event was referred to as the duration of efficacy (DE). By life table analysis, the DE for the treatment group was 100% at 30 days, 91% at 60 days, 85% at 90 days, 72% at 180 days, and 17% at 360 days. Comparison of the characteristics and results obtained in the treatment group and that of the concurrent control group revealed no significant difference in any parameter prior to treatment, in the response to PTVA, or in the DE of the procedure performed. It was concluded that the stent offered no advantage in the treatment of the graft-vein anastomosis stenotic lesion affecting PTFE dialysis access grafts.

Author information

Author/s: Beathard, G A (GA);

Affiliation: Austin Diagnostic Clinic, Texas.

Journal and publication information

Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal: Kidney international (Kidney Int), published in UNITED STATES. (Language: eng)

Reference: 1993-Apr; vol 43 (issue 4) : pp 872-7

Dates: Created 1993/05/27; Completed 1993/05/27; Revised 2006/11/15;

PMID: 8479123, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Angioplasty - instrumentation; methods Arteriovenous Shunt, Surgical - adverse effects Graft Occlusion, Vascular - surgery Humans

Humans Polytetrafluoroethylene Renal Dialysis - adverse effects Stents

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Polytetrafluoroethylene (9002-84-0)

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