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| Research article summary (published 30 May 1993): |
Heart rate/stroke volume relationship during upright exercise in long-term diabetics.
Full Abstract
The changes in stroke volume (SV) during upright exercise were studied in 20 insulin-dependent diabetics (IDDM) and 20 age- and sex-matched controls. None of the diabetics had any cardiovascular symptoms. In addition, tests of autonomic function were conducted in the diabetics, assessing changes in heart rate (HR) during deep breathing and the Valsalva maneuver. During exercise the SV in the controls gradually increased and then remained essentially unchanged until maximum HR was achieved. Seven of the diabetics failed to sustain an initial increase in SV (fall > 15%), eight showed a "delayed" increase in SV, and the remaining five demonstrated an increasing SV over the range from rest to peak exercise. Abnormal autonomic function results were found during deep breathing (four diabetics) and the Valsalva maneuver (four diabetics). Findings indicate that cardiac function could be abnormal in IDDM without evidence of autonomic dysfunction. This abnormality could be due to a specific cardiomyopathy.
Author information
Author/s: Haennel, R G (RG); Teo, K K (KK); Suthijumroon, A (A); Senaratne, M P (MP); Hetherington, M (M); Ryan, E (E); Kappagoda, C T (CT);
Affiliation: Faculty of Physical Activity Studies, University of Regina, Saskatchewan.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Canadian journal of applied physiology = Revue canadienne de physiologie appliquée (Can J Appl Physiol), published in UNITED STATES. (Language: eng)
Reference: 1993-Jun; vol 18 (issue 2) : pp 148-62
Dates: Created 1993/07/22; Completed 1993/07/22; Revised 2008/11/21;
PMID: 8513288, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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