Effect of titanium on selected oral bacterial species in vitro.

Full Abstract

Titanium granules were tested for their antibacterial effect on strains of Streptococcus sanguis, Streptococcus mitis, Actinomyces naeslundii, Haemophilus parainfluenzae, Fusobacterium spp. and Prevotella intermedia in comparison with amalgam and two of its components, copper and tin. Glass beads were used as controls. The number of viable bacteria was estimated in samples exposed to the various materials for 1, 3, 6 and 24 h, respectively, and the viable counts were related to the baseline value. Titanium showed low antibacterial effect on the species tested. Copper and amalgam showed an expressed toxicity to all species and differed significantly from titanium and glass particles. Gram positive Streptococcus spp. and A. naeslundii showed a lower susceptibility to the metals than the Gram negative species. The antibacterial effect of copper and amalgam test particles on S. sanguis and P. intermedia was significantly decreased in the presence of serum. This study showed that some metals have a toxic effect in vitro on oral bacteria, a fact that may play a role in plaque formation when these materials are used for dental restorations. Titanium did not have a similar antibacterial effect.

Author information

Author/s: Leonhardt, A (A); Dahlen, G (G);

Affiliation: Department of Oral Microbiology, Faculty of Obdontology, Goeteborg University, Sweden.

Journal and publication information

Publication Type: Comparative Study; Journal Article

Journal: European journal of oral sciences (Eur J Oral Sci), published in DENMARK. (Language: eng)

Reference: 1995-Dec; vol 103 (issue 6) : pp 382-7

Dates: Created 1996/12/03; Completed 1996/12/03; Revised 2006/11/15;

PMID: 8747674, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Actinomyces - drug effects
Anti-Infective Agents, Local - pharmacology
Bacteria - drug effects
Blood
Colony Count, Microbial
Copper - pharmacology; toxicity
Culture Media
Dental Amalgam - pharmacology; toxicity
Dental Materials - pharmacology; toxicity
Dental Plaque - microbiology

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Anti-Infective Agents, Local (0) ; Culture Media (0) ; Dental Materials (0) ; Tin (7440-31-5) ; Titanium (7440-32-6) ; Copper (7440-50-8) ; Dental Amalgam (8049-85-2)

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